Researchers identify 33 new genetic variants associated with bipolar disorder

Eduard Vieta and Josep Antoni Ramos-Quiroga.
Eduard Vieta and Josep Antoni Ramos-Quiroga.
Eduard Vieta and Josep Antoni Ramos-Quiroga. The largest conducted study to date on bipolar disorder inheritability has enabled researchers to identify 33 new genetic variants related to this mental disorder, which is a turning point to step forward in the discovery of therapeutical targets and drugs to treat it. The study has been co-led by Eduard Vieta, professor at the Department of Medicine and member of the Institute of Neurosciences of the UB and Hospital Clínic-IDIBAPS, and Josep Antoni Ramos-Quiroga, from the Department of Psychiatry at the Vall d'Hebron Barcelona University Campus and the Vall d'Hebron Research Institute (VHIR). Both researchers are also members of the Mental Health Networking Biomedical Research Centre (CIBERSAM). This international collaborative research study has been carried out within the framework of the team working on bipolar disorder in the Psychiatrics Genomics Consortium. Bipolar disorder is a complex mental disorder that features the pathological shifts of depressive episodes and episodes of an opposite mood, known as mania and hypomania . Between 40 and 50 people worldwide are estimated to suffer from this disorder.
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