news 2023

A clinical trial carried out by Hospital del Mar, Pompeu Fabra University, the Health Research Institute of Santiago de Compostela and the Pere Virgili Health Park investigated the efficacy and safety of a medicine for outpatients with COVID-19. The treatment acts on the replication mechanism of SARS-CoV-2, the virus responsible for the disease, and reduces the severity and duration of some of the symptoms.

A team from the Universidad Autónoma de Madrid (UAM) and the Hospital Universitario de la Princesa has identified previously unknown alterations in a subtype of immune system cells in patients with Sjögren's syndrome. The finding, published in The EMBO Journal , could open up new avenues for the development of more specific and effective treatments against this chronic autoimmune disease.

A Universitat de València (UV) and IIS La Fe team, integrated in the Biomedical Research Centre in Network of Hepatic and Digestive Diseases (CIBERehd), has proven the potential of metabolomics for the study of hepatotoxicity of new medical drugs thanks to its relevance as a discovery tool of new biomarkers.

A team of pharmacogenetics experts from the Universidad Autónoma de Madrid (UAM) and the Hospital Universitario de La Princesa have questioned the clinical utility of a biomarker that has been assumed to hold promise for personalized drug treatments. The results, published in the journal Clinical Pharmacology and Therapeutics , highlight the importance of rigorous and continuous evaluation of pharmacogenetic biomarkers prior to their implementation in clinical practice.

IBiS research has discovered new phenotypes of neural tube defects in the loop-tail mouse model resistant to folic acid supplementation. These findings not only broaden our understanding of the disease, but provide valuable tools for future research into the prevention of conditions such as spina bifida.

According to an international scientific study in which the universities of Zaragoza and Carlos III de Madrid are participating 11/20/23 In order to minimise the impact of a pandemic on the economy, which would be more effective: a lockdown or letting individuals spontaneously reduce their risk of infection? Research recently published in the journal Nature Human Behaviour by Spanish scientists suggests that these two widely debated options lead to similar outcomes; that is, the economy will always be damaged, but at least a lockdown will save more lives.

How does a person with physical and sensory limitations feel? What are the restrictions for an elderly person who sees and hears poorly and whose joints are no longer what they used to be? Clinical researchers, especially those who deal with patients, have asked themselves that question and have tried to find the answer, and one of them has been the design of an aging and disability simulation suit.

Groundbreaking research reveals combining data supercharges mental health crisis prediction Groundbreaking research reveals combining data supercharges mental health crisis prediction In an extensive 8-year study published in Cell Reports Medicine conducted by Koa Health, researchers closely monitored 59,750 de-identified patient records, with a primary goal of predicting mental health crises occurring within a 28-day window.

A research team led by the Institute of Evolutionary Biology (IBE) and Pompeu Fabra University (UPF) has identified the most widespread genetic contribution by Denisovans to date. The study reveals that the genetic variant observed, which affects zinc regulation, could have signified an evolutionary advantage in our ancestors' adaptation to the cold.

Researchers from the Institute of Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council (CSIC), have studied the mechanism by which the body's antibodies target coxsackievirus B3, which causes serious heart inflammation in humans.

Researchers at the Autonomous University of Madrid (UAM) have discovered that lactoferrin, a protein with anti-inflammatory and antimicrobial properties, exhibits significant antiviral activity against coronaviruses such as SARS-CoV-2. This finding, published in the journal Viruses , could open new avenues for the treatment and prevention of viral infections.

Research conducted in a mouse model identifies the neurobiological mechanism responsible for alterations in the memory of young individuals exposed to alcohol during pregnancy and lactation. This study proposes a therapy that can reverse the deficit, paving the way for treating a disorder that is underdiagnosed in humans.

An article published by the full professor of the Department of Paediatrics, Obstetrics and Gynaecology of the University of Valencia (UV) Carlos Simón and his research team (UV, INCLIVA and Carlos Simón Foundation) in the journal Nature Communications , describes for the first time the cellular alterations responsible for Asherman's Syndrome at the single cell level.

Rosario Gil: "In Valencia we are developing a system to fight the tiger mosquito plague with the bacterium Wolbachia " Rosario Gil García is a professor at the University of Valencia (UV) in the Department of Genetics and a researcher at the Institute of Integrative Systems Biology (I2SysBio), a joint centre of the UV and the Spanish National Research Council (CSIC).

Reducing the population of the Asian tiger mosquito in Valencia by inoculating males with the Wolbachia bacteria investigated A team of researchers from the University of Valencia (UV) is working on

Pioneering research by the University of Valencia and the CSIC uses bacteria viruses against Xylella fastidiosa in the Balearic Islands Pilar Domingo-Calap, researcher at the Institute of Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia (UV) and the Spanish National Research Council (CSIC), directs research with phages (bacterial viruses) that has started treating crop plants affected by the bacteria Xylella fastidiosa in the Balearic Islands.

Researchers from the Autonomous University of Madrid (UAM) and CSIC have studied the effect of lamivudine, a drug used in the treatment of HIV, in a transgenic model of Alzheimer's disease. The results, published in the International Journal of Molecular Sciences , suggest that retranscriptase inhibitors may be a promising strategy to be developed in the field of neurodegenerative diseases.

Empowering Europe against infectious diseases: innovative framework to tackle climate-driven health risks Empowering Europe against infectious diseases: innovative framework to tackle climate-driven h

A research team from the Universidad Carlos III de Madrid (UC3M), together with University College London in the United Kingdom, has carried out a study to analyse how chronic pain affects each patient's body. Within this framework, a deep learning method has been developed to analyse the biometric data of people with chronic conditions.

Researchers from the University of Valencia and the INCLIVA Health Research Institute (Valencia Clinical Hospital) have analysed the possible effects of the presence of cytomegalovirus (CMV) in the blood of patients receiving CAR-T therapies, a form of immunotherapy that has been shown to be effective in certain types of haematological cancer.