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Health - Pharmacology - 17.07.2023

Researchers study the effects of cytomegalovirus in the blood of patients with CAR-T therapies against some cancers
Researchers from the University of Valencia and the INCLIVA Health Research Institute (Valencia Clinical Hospital) have analysed the possible effects of the presence of cytomegalovirus (CMV) in the blood of patients receiving CAR-T therapies, a form of immunotherapy that has been shown to be effective in certain types of haematological cancer.

Pharmacology - 11.07.2023

Determined the patterns of drug use in Valencia from the analysis of wastewater
A study by the Centre for Research on Desertification (CIDE, UV-CSIC-GVA) has evaluated, through the analysis of wastewater, drug use in the city of Valencia during the period from 2011 to 2020. Cannabis, tobacco, and cocaine were the most consumed, especially during weekends and festive periods, in accordance with the EU estimates.

Pharmacology - Health - 29.06.2023

Culmination of the eTRANSAFE project to share data on the safety of medicines
The project, jointly coordinated by UPF professor Ferran Sanz, has enjoyed the participation of numerous members of the GRIB; the UPF research programme in Medical Bioinformatics and the Hospital del Mar Research Institute, as well as the spinoff Med Bioinformatics Solutions, which emerged from the same programme.

Life Sciences - Pharmacology - 08.06.2023

Discovered that the interaction of opioids with the brain’s immunity influences anxiety and addiction in cases of pain
A research by the Department of Pharmacy and Pharmaceutical Technology and Parasitology, and the Institute of Biotechnology and Biomedicine (BIOTECMED) of the University of Valencia (UV), reveals that

Health - Pharmacology - 19.04.2023

Antonio Cano investigates a drug that reduces menopausal hot flashes
Antonio Cano, full professor of the Department of Paediatrics, Obstetrics and Gynaecology of the University of Valencia and coordinator of the Women's Health Research Group at the INCLIVA Health Research Institute, of the Clinical Hospital of Valencia, participates in an international investigation published in The Lancet magazine that has released the results of the SKYLIGHT 1 clinical trial.

Health - Pharmacology - 27.03.2023

Non-invasive localisation of breast lesions for surgical planning
A research group from the Universidad Carlos III de Madrid (UC3M) has participated in the development of a new technique based on medical imaging which makes it possible to non-invasively estimate the location of a tumour in the surgical position required for breast cancer surgery.

Health - Pharmacology - 13.03.2023

New tool to diagnose and assess the severity of sarcopenia
Recerca La sarcopènia és una malaltia degenerativa caracteritzada per una disminució patològica de la força muscular que afecta especialment les persones de més edat. Investigadors de la Universitat de Barcelona han desenvolupat una nova eina per avaluar la presència i la gravetat d'aquesta insuficiència muscular.

Pharmacology - Health - 28.02.2023

BIOTECMED researchers review treatments under development for the rare disease myotonic dystrophy type 1
Researchers Rubén Artero and Arturo López, from the University Institute of Biotechnology and Biomedicine (BIOTECMED) of the University of Valencia (UV), and from the INCLIVA Translational Genomics Research Group, have just published a paper on the treatments in Drug Discovery Today about the rare disease myotonic dystrophy type 1 (DM1).

Pharmacology - Life Sciences - 26.01.2023

To improve existing antibiotics and develop new antimicrobial treatments
Recerca The lack of effective antibiotics is an increasingly serious threat to global health. In recent decades, only a few new antimicrobial agents have been able to reach the market. Designing new functionalities for already known antibiotics —or those that have fallen out of use due to toxicity— is one of the strategies to make up for this drug shortage.

Physics - Pharmacology - 10.01.2023

New nanotransporter for drug delivery inside cells
A new study by the University of Barcelona has analized the viability of a new nanomolecule as drug delivery vehicle. The results, published in the journal Colloids and Surfaces B: Biointerfaces , show that liposomes designed by researchers are able to transport and deliver an anticancer drug that has been used as a model inside the cells.

Health - Pharmacology - 16.12.2022

The most common type 2 diabetes drug needs the action of a cellular-stress-response protein to make effect
Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

Health - Pharmacology - 14.12.2022

The IFIC collaborates in the first international manual of supportive therapies in cancer patients
A group of researchers from the Institute of Corpuscular Physics (IFIC, UV-CSIC) has collaborated in the publication of the first international manual of supportive therapies for cancer patients.

Pharmacology - Health - 05.12.2022

A team from the UB and IBUB reveals the extraordinary plasticity of the glucocorticoid receptor
Glucocorticoids —such as cortisone— are among the most widely used anti-inflammatory drugs, and are used to treat asthma, psoriasis, organ transplantation and even COVID-19. Regarding their pharmacological action, the activity of the glucocorticoid receptor (GR) is crucial. The GR is a transcription factor that regulates vital processes in human physiology.

Pharmacology - Health - 29.06.2022

Artificial intelligence techniques used to obtain antibiotic resistance patterns
The Universidad Carlos III de Madrid (UC3M) is conducting research that analyses antibiotic resistance patterns with the aim of finding trends that can help decide which treatment to apply to each type of patient and stop the spread of bacteria. This study, recently published in the scientific journal Nature Communications, has been carried out together with the University of Exeter, the University of Birmingham (both in the United Kingdom) and the Westmead Hospital in Sydney (Australia).

Health - Pharmacology - 31.05.2022

How have hepatocellular carcinoma treatments improved?
Researchers of the University of Barcelona and Hospital Clínic-IDIBAPS published a review article in the journal Nature Cancer in which they describe the molecular alterations observed in the evolution of the hepatocellular carcinoma -the most common type of liver cancerand propose a sequencing strategy for systemic treatment incorporating all the approved therapies to date.

Health - Pharmacology - 16.05.2022

In osteoarthritis of the knee, the same treatment does not work for everyone. How to know when to operate?
Researchers from the UPF BCN MedTech research unit, the IMIM-Hospital del Mar and the Hospital del Mar have studied the relationship between clinical treatment options for osteoarthritis of the knee and the functionality, speed and forces involved in each patient's stride. The results reveal that two patients with the same symptoms may need different treatment depending on their age and body mass index.

Life Sciences - Pharmacology - 05.05.2022

A paper of the Universitat de València and IIS La Fe about stem cells differentiation to hepatocytes appears on the cover of the Journal of Proteome Research
The research team of the Mixed Unit Universitat de Valéncia-IIS La Fe of Experimental Hepatology and Hepatic Transplantation has published a paper in the Journal of Proteome Research, a peer-reviewed scientific journal of the American Chemical Society.

Health - Pharmacology - 27.04.2022

Researchers design nanochips that penetrate inside cells as mechanical drugs
A research team put devices of 50 nanometre-thick —one thousandth of a hair's part— inside living cells in order to find their division process and alter it, and even destroy cells. The new study, which sheds light on the exploration pathways in the field of nanomedicine, includes the participation of the researchers Lluïsa Pérez-Garcia and Ezhil Amirthalingam, from the Faculty of Pharmacy and Food Sciences and the Institute of Nanoscience and Nanotechnology of the University of Barcelona ( IN2UB ).

Life Sciences - Pharmacology - 24.03.2022

A simple way to study the mouse epigenome
The laboratory mouse is an experimental model widely used in preclinical biomedical research. Researchers can determine the efficiency of drugs and their possible adverse effects in these animals, and they can mimic human diseases in order to find the mechanisms of their emergence and identify treatments to fight them.

Health - Pharmacology - 17.03.2022

Radical increase in the effectiveness of breast cancer immunotherapy
A study published in the journal Nature Cancer has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumours, triple-negative breast cancer. This subtype, although accounting for only 15% of cases, is one of the most rapidly progressing and affects younger patients.